波谱学杂志 ›› 1994, Vol. 11 ›› Issue (1): 27-33.

• 研究论文 • 上一篇    下一篇

测定核间距的不对称2D NOESY方法2.Cis-Pt(NH3)2(Guo)2Cl2的不对称2D NOESY实验研究

缪希茄1,2, 韩秀文1, 胡皆汉1   

  1. 1. 中国科学院大连化学物理研究所, 大连 116023;
    2. 中国科学院武汉物理研究所波谱与原子分子物理国家重点实验室, 武汉 430071
  • 收稿日期:1992-06-25 修回日期:1993-04-05 出版日期:1994-03-05 发布日期:2018-01-20

DKTERMINATION OF INTERNUCLEAR DISTANCES FROM THE NONSYMMETRIC 2D NOESY METHOD 2.The Nonsymmetric 2D NOESY Experiment for Cis-Pt(NH3)2(Guo)2Cl2

Miao Xijia1,2, Han Xiuwen1, Hu Jiehan1   

  1. 1. Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023;
    2. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics, The Chinese Academy of Sciences, Wuhan 430071
  • Received:1992-06-25 Revised:1993-04-05 Online:1994-03-05 Published:2018-01-20

摘要: 应用不对称2DNOESHY实验方法研究了顺铂配合物Cis-Pt (NH3)2(Guo)2Cl2的水溶液中的构象,表明鸟苷同铂配合后其糖环构象发生明显的变化。

关键词: 不对称2DNOESY, 核间距, 顺铂配合物Cis-Pt (NH3)2(Guo)2Cl2, 溶液构象

Abstract: The nonsymmetric 2D NOESY experiment has been used to investigate the conformation of cis-platinum complex Pt(NH3)2(Guo)2Cl2 in deuterium aqueous solution. The results showed that the cyclic conformation of sugar for guanosine in Cis-Pt(NH3)2(Guo)2Cl2 changes obviously as guanosine coordinates toward platinum.

Key words: Nonsymmetric 2D NOESY, Internuclear distance, Solution conformation, Cis-platinum complex Pt (NH3)2(Guo)2Cl2