fMRI在经颅直流电刺激研究中的应用进展

doi:10.11938/cjmr20202805

摘要/Abstract

摘要： 经颅直流电刺激（tDCS）是一种新颖的神经系统疾病治疗手段，可非侵入性调控中枢神经活动.它具有安全、成本低、疗效显著等特点，因此在神经科学等领域被大量研究和应用.功能磁共振成像（fMRI）具备高时空分辨率的优势，近年来被广泛用于tDCS治疗效果的评估及其作用机制的研究.本文从临床研究与动物模型实验两方面总结fMRI技术应用于tDCS研究中的最新进展，并讨论其应用前景.

关键词: 经颅直流电刺激（tDCS）, 功能磁共振成像（fMRI）, 神经系统

Abstract: Transcranial direct current stimulation (tDCS) noninvasively modulates the excitability of the brain, and is a promising method for treating diseases in the central nervous system. tDCS is safe, effective and affordable, and has been increasingly applied in neuroscience research. Functional magnetic resonance imaging (fMRI) is a widely-used tool to evaluate the therapeutic effects and the underlying neural mechanisms of tDCS. Herein we briefly reviewed the progresses of applications of fMRI in tDCS research. Both clinical trials and animal model experiments were discussed, as well as the perspectives of future applications.

Key words: transcranial direct current stimulation (tDCS), functional magnetic resonance imaging (fMRI), central nervous system

中图分类号:

O482.53

程力维, 王璐璐, 钟凯. fMRI在经颅直流电刺激研究中的应用进展[J]. 波谱学杂志, 2020, 37(4): 533-546.

CHENG Li-wei, WANG Lu-lu, ZHONG Kai. Application of fMRI in Transcranial Direct Current Stimulation Researches[J]. Chinese Journal of Magnetic Resonance, 2020, 37(4): 533-546.

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