波谱学杂志 ›› 2016, Vol. 33 ›› Issue (1): 54-65.doi: 10.11938/cjmr20160105

• 谱仪研制技术进展专栏 • 上一篇    下一篇

一种用于fMRI的温度觉刺激装置的设计与验证

董涛1,2,3, 梁思1,2,3, 王慧3, 杨晓冬3   

  1. 1. 中国科学院 长春光学精密机械与物理研究所, 吉林 长春 130033;
    2. 中国科学院大学, 北京 100049;
    3. 中国科学院 苏州生物医学工程技术研究所, 江苏 苏州 215163
  • 收稿日期:2015-04-02 修回日期:2016-01-22 出版日期:2016-03-05 发布日期:2016-03-05
  • 通讯作者: 杨晓冬,电话:0512-69588133,E-mail:xiaodong.yang@sibet.ac.cn. E-mail:xiaodong.yang@sibet.ac.cn
  • 作者简介:董涛(1990-),男,湖北荆州人,硕士研究生,机械工程专业.
  • 基金资助:

    中科院科研装备研制资助项目(YZ201253),江苏省自然科学基金资助项目(BK20131171).

Design and Evaluation of a Caloric Stimulation Device for fMRI Studies

DONG Tao1,2,3, LIANG Si1,2,3, WANG Hui3, YANG Xiao-dong3   

  1. 1. Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China;
    2. University of Chinese Academy of Sciences, Beijing 100049, China;
    3. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
  • Received:2015-04-02 Revised:2016-01-22 Online:2016-03-05 Published:2016-03-05

摘要:

介绍了一种用于功能磁共振成像(fMRI)的温度觉刺激装置的设计与验证,该装置能够用于fMRI温度觉的脑功能研究,满足温度觉fMRI实验的自动化刺激要求.整个刺激装置设计了以微控制器为核心的控制电路,通过数据采集卡能够与上位机LabVIEW软件进行数据通讯,并将获取的数据通过特定的串口协议传递给数字PID温控模块,实现对刺激端温度的精确调控.最后,使用该刺激装置对多名被试进行了温度觉的脑功能实验,实验结果验证了该设计的可行性.

关键词: 功能磁共振成像(fMRI), 刺激装置, LabVIEW, 温度觉刺激

Abstract:

In this study, we designed and verified a computer-controlled caloric stimulation device for delivering caloric stimulation in functional magnetic resonance imaging (fMRI) environment. The stimulation device consists of a caloric stimulation generation unit and a control unit. The control system unit includes a microcontroller module which can process stimulation command written in LabVIEW, and then transfer the stimulation sequence to a digital PID temperature control module to achieve exact caloric stimulation via a small peltier-pod. The performance of the device was evaluated with caloric stimulation fMRI experiments, and the results from 5 test subjects demonstrated the reliability of the device.

Key words: fMRI, stimulation device, LabVIEW, caloric stimulation

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