Chinese Journal of Magnetic Resonance ›› 2016, Vol. 33 ›› Issue (3): 502-513.doi: 10.11938/cjmr20160315

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Pure Shift Proton NMR Spectroscopy and Its Applications

ZHOU Qiu-ju1,2, XIANG Jun-feng2,3, TANG Ya-lin2, CUI Jie2, WU Ning-ning2   

  1. 1. Xinyang Normal University, Xinyang 464000, China;
    2. Institute of Chemistry, Chinese Academy Sciences, Beijing 100190, China;
    3. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2015-10-22 Revised:2016-07-10 Online:2016-09-05 Published:2016-09-05

Abstract:

J coupling gives rise to spectral multiplets (i.e. resonance from one spin is split into a group of equally spaced lines placed symmetrically around the chemical shift). Such spectral splitting contains information on molecular structure, and is therefore useful for structural elucidation. However, when the number of spin increases and many spectral multiplets are present, the spectra, especially proton spectra, could become very crowded, making structural elucidation and quantitative analysis difficult. Using the pure shift (i.e., broadband homonuclear decoupling) proton NMR technique, one could collapse spectral multiplets into singlets, and obtain spectra containing only chemical shift information. In this paper, we give brief introductions to three most widely used pure shift proton NMR techniques, namely BIRD, ZS, and PSYCHE, and describe typical applications of such techniques.

Key words: ZS, PSYCHE, J coupling, pure shift (broadband homonuclear decoupling) 1H NMR spectroscopy, BIRD

CLC Number: