Chinese Journal of Magnetic Resonance

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Current State and Future of Optogenetic Functional Magnetic Resonance Imaging

WU Rui-qi1,3,LI Bo1,3,LIU Yue2,XU Fu-qiang1,2*
 
  

  1. 1. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics (Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences), Wuhan 430071, China; 2. Wuhan National Laboratory of Optoelectronics, Wuhan 430074, China; 3. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2013-06-27 Revised:2013-07-17 Online:2014-06-05 Published:2014-06-05
  • About author:*Corresponding author:XU Fu-qiang, Tel: 027-87197091. E-mail: fuqiang.xu@wipm.ac.cn.
  • Supported by:

    国家自然科学基金资助项目(91132307/H09, 31171061/C090208和20921004), 国家科技部支撑计划资助项目(2012BAI23B02).

Abstract:

Functional magnetic resonance imaging (fMRI) is the mainstay of neuroimaging approach in neuroscience after a rapid development during the past twenty years. The optogenetic fMRI (ofMRI) is a novel technology that combines optogenetics and fMRI, which has the potential to be used to analyze the functional roles and properties of specific neurons and/or specific neurocircuits in the whole brain. It opens a new vista for exploring human brain networks both functionally and structurally.

Key words: functional magnetic resonance image, optogenetics, blood oxygen level dependent, functional connectivity

CLC Number: