Chinese Journal of Magnetic Resonance

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Quantitative Susceptibility Mapping

WANG A-li1,LIN Jian-zhong2,LIU Wei-jun3,CAI Cong-bo3*,CHEN Zhong1   

  1. 1. Department of Electronic Science, Xiamen University, Fujian Key Laboratory of Plasma and Magnetic Resonance, Xiamen 361005, China;
    2. Zhongshan Hospital Xiamen University, Xiamen 361005, China;
    3. Department of Communication Engineering, Xiamen University, Xiamen 361005, China
  • Received:2013-11-06 Revised:2013-11-30 Online:2014-03-05 Published:2014-03-05
  • About author:*Corresponding author:CAI Cong-bo, Tel: 0592-2087539, E-mail: cbcai@xmu.edu.cn.
  • Supported by:

    国家自然科学基金资助项目(81171331, 11174239),中央高校基本业务费资助项目(2010121101).

Abstract:

Phase images of magnetic resonance imaging (MRI) contain abundant information about local susceptibility changes among different types of tissues, and getting phase images requires no additional scan time. The diagnosis of cerebrovascular diseases and nervous system diseases may benefit from the quantification of paramagnetic substances in tissues. Quantitative susceptibility mapping (QSM), which uses the local phase information, has become a hot topic in basic and clinical studies. Paramagnetic substances in tissues cause local susceptibility changes and lead to local inhomogeneous magnetic field. However, the reconstruction of susceptibility distribution from induced magnetic field is an ill-posed inverse problem, and there are still many problems to be
solved at present. This article focuses on the theory of QSM, reconstruction methods and its applications in MRI.

Key words: QSM, image reconstruction, background magnetic field, phase image

CLC Number: