用核磁共振研究和确定乌拉尔甘草中一种新成分的化学结构

波谱学杂志 ›› 1990, Vol. 7 ›› Issue (1): 11-16.

用核磁共振研究和确定乌拉尔甘草中一种新成分的化学结构

高从元, 乔梁, 贾琦, 张志亮

北京医科大学波谱分析室

收稿日期:1988-09-08 修回日期:1989-05-10 出版日期:1990-03-05 发布日期:2018-01-23

STUDY AND IDENTIFICATION OF THE CHEMICAL STRUCTURE OF A NEW COMPONENT IN GLYCYRRIZA URALENSIS FISCH BY NMR METHOD

Gao Congyuan, Qiao Liang, Jia Qi, Zhang Zhiliang

Beijing Medical University, Beijing 100083

Received:1988-09-08 Revised:1989-05-10 Online:1990-03-05 Published:2018-01-23

摘要/Abstract

摘要： 本文报告了用多种核磁共振实验方法并结合其它结构信息,研究并首次确定了内蒙产的乌拉尔甘草(Glycyrrhiza uralensis Fisch)中一种新甘草三萜内酯的化学结构并命名为甘乌内酯(Glyuranolide)。

关键词: 乌拉尔甘草, 甘草三萜内酯, 甘乌内酯, 同核二维相关氢谱, 同核二维欧沃豪斯谱, 非灵敏核极化转移增强法

Abstract: Various NMR spectra (including NOE, SD, BB, INEPT, SR, COSY, and NOESY etc.) were used in the study and identification of the chemical structure of a new glycyrrizic triterpenoid lactone which was extracted from Glycyrrhiza uralensis Fisch collected in Inner Mongolia. This new component was named Glyuranolide (3,22-dihydroxy-11-oxo-12-oleanene-14-methoxycarbonyl-29-dioic acid-22-lactone).

Key words: Glycyrriza uralensis Fisch, Glycyrrizic triterpenoid lacton, Glyuranolide, COSY (Correlated 2D spectroscopy), NOESY (Nuclear Overhauser effect spectroscopy), INEPT (Insensitive nuclei enhancement of polarization transfer), ¹³C-NMR, NOE

高从元, 乔梁, 贾琦, 张志亮. 用核磁共振研究和确定乌拉尔甘草中一种新成分的化学结构[J]. 波谱学杂志, 1990, 7(1): 11-16.

Gao Congyuan, Qiao Liang, Jia Qi, Zhang Zhiliang. STUDY AND IDENTIFICATION OF THE CHEMICAL STRUCTURE OF A NEW COMPONENT IN GLYCYRRIZA URALENSIS FISCH BY NMR METHOD[J]. Chinese Journal of Magnetic Resonance, 1990, 7(1): 11-16.

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