利用二维接力相关谱和J分解谱对里杜霉素质子信号的归属

波谱学杂志 ›› 1989, Vol. 6 ›› Issue (1): 29-34.

利用二维接力相关谱和J分解谱对里杜霉素质子信号的归属

俞汉钢, 刘树勋

中科院上海药物研究所

收稿日期:1987-09-11 修回日期:1987-12-19 出版日期:1989-03-05 发布日期:2018-01-22

COMPLETE ASSIGNMENT OF PROTON SIGNALS IN LIVIDOMYCIN USING TWO-DIMENSIONAL RELAY CORRELATION SPECTRA AND J-RESOLVED SPECTRUM

Yu Hangang, Liu Shuxun

Shanghai Institute of Materia Medica, Academia Sinica

Received:1987-09-11 Revised:1987-12-19 Online:1989-03-05 Published:2018-01-22

摘要/Abstract

摘要： 本文采用二维接力相关技术(单接力和三接力COSY)和J分解谱对氨基糖苷类化合物里杜霉素的全部质子信号进行了归属,为进一步测定里杜霉素的构型和构象打下了基础.

关键词: 接力相关谱, 里杜霉素

Abstract: The assignment of protons in Lividomycin is difficult in the range 3.50-4.00ppm because of severe overlap of their signals. In this work, the RELAY-COSY, triple-RELAY COSY and the high resolution J-resolved spectrum were used and showed to be very useful for solving the problem described above. Furthermore, it provides a basis for elucidating the configuration and conformation of Lividomycin.

Key words: Relay correlation spectrum, Lividomycin

俞汉钢, 刘树勋. 利用二维接力相关谱和J分解谱对里杜霉素质子信号的归属[J]. 波谱学杂志, 1989, 6(1): 29-34.

Yu Hangang, Liu Shuxun. COMPLETE ASSIGNMENT OF PROTON SIGNALS IN LIVIDOMYCIN USING TWO-DIMENSIONAL RELAY CORRELATION SPECTRA AND J-RESOLVED SPECTRUM[J]. Chinese Journal of Magnetic Resonance, 1989, 6(1): 29-34.