HMQC-TOCSY技术在植物环肽和配糖体中的应用

波谱学杂志 ›› 1999, Vol. 16 ›› Issue (4): 295-301.

HMQC-TOCSY技术在植物环肽和配糖体中的应用

滕荣伟¹, 王德祖¹, 李朝明¹, 丁中涛², 杨崇仁¹

1. 中国科学院昆明植物研究所, 昆明 650204;
2. 云南大学化学系, 昆明 650091

收稿日期:1999-03-19 修回日期:1999-04-19 出版日期:1999-08-05 发布日期:2018-01-11
作者简介:滕荣伟,男,1975年出生,在读博士
基金资助:
中科院昆明植物所植物化学开放实验室资助项目

THE APPLICATION OF HMQC-TOCSY TO THE PLANT GLYCOSIDES AND PLANT CYCLOPEPTIDES

Teng Rongwei¹, Wang Dezu¹, Li Chaoming¹, Ding Zhongtao², Yang Chongren¹

1. Kunming Institute of Botany, The Chinese Academic of Sciences, Kunming 650204;
2. Yunnan University, Department of Chemistry, Kunming 6500091

Received:1999-03-19 Revised:1999-04-19 Online:1999-08-05 Published:2018-01-11

摘要/Abstract

摘要： 核磁共振HMQC-TOCSY二维技术可在氢谱方向和碳谱方向分别得到独立的自旋系统内氢核和碳核的全相关信息.该技术对于分子内具有多个自旋系统的植物环肽和配糖体的结构解析尤为适用.本文以环肽annosquamosin A和三萜皂甙prostratoside A为例说明该技术在这两类化合物中的应用.

关键词: HMQC-TOCSY, 植物环肽, 配糖体, AnnosquamosinA, ProstratosideA

Abstract: HMQC-TOCSY experiment is a useful 2D NMR technique for elucidating structures of organic molecules that possess independent spin systems. From HMQC-TOCSY spectrum, we can obtain information of all the proton connectivities in the F₂ dimension and information of the carbon connectivity in the F₁ dimension for a given spin system, so the chemical shifts of both proton and carbon can be simultaneously assigned. In this paper, two examples, annosquamosin A, which is a cyclopeptide, and prostratoside A, which is a triterpenoidal saponin, are given to demonstrate the application of this technique to the natural products.

Key words: HMQC-TOCSY, Annosquamosin A, Prostratoside A

滕荣伟, 王德祖, 李朝明, 丁中涛, 杨崇仁. HMQC-TOCSY技术在植物环肽和配糖体中的应用[J]. 波谱学杂志, 1999, 16(4): 295-301.

Teng Rongwei, Wang Dezu, Li Chaoming, Ding Zhongtao, Yang Chongren. THE APPLICATION OF HMQC-TOCSY TO THE PLANT GLYCOSIDES AND PLANT CYCLOPEPTIDES[J]. Chinese Journal of Magnetic Resonance, 1999, 16(4): 295-301.

[1]	滕荣伟，丁中涛，何以能，杨崇仁，王德祖*. 二蕊荷莲豆环肽B的NMR应用研究[J]. 波谱学杂志, 2003, 20(1): 43-50.
[2]	滕荣伟, 李海舟, 王德祖, 何以能, 杨崇仁. 三个原人参二醇型单糖链配糖体的NMR信号全指定[J]. 波谱学杂志, 2000, 17(6): 461-468.
[3]	滕荣伟, 钟惠明, 陈昌祥, 王德祖. 三萜皂甙Tanguticoside A的NMR碳氢化学位移全指定[J]. 波谱学杂志, 1999, 16(5): 389-394.