高性能核磁共振弛豫分析仪匀场系统的设计与实现

doi:10.11938/cjmr20170111

波谱学杂志 ›› 2017, Vol. 34 ›› Issue (1): 87-99.doi: 10.11938/cjmr20170111

• 低场磁共振技术与应用专栏 • 上一篇下一篇

高性能核磁共振弛豫分析仪匀场系统的设计与实现

陈珊珊^1,2, 夏天², 毕昕², 苗志英¹, 杨培强³, 汪红志^1,2, 戴曙光¹

1. 上海理工大学光电信息与计算机工程学院, 上海 200093;
2. 上海健康医学院, 上海 201318;
3. 苏州纽迈电子科技有限公司, 江苏苏州 215163

收稿日期:2015-12-21 修回日期:2017-01-04 出版日期:2017-03-05 发布日期:2017-03-05
通讯作者: 汪红志,Tel:021-65885652,E-mail:wanghzhi2000@sina.com;戴曙光,Tel:021-55272982,E-mail:usstdsg@163.com E-mail:wanghzhi2000@sina.com;usstdsg@163.com
基金资助:
国家重大科学仪器设备开发专项（2013YQ170463）

Design and Implementation of An Active Shimming System for Low Field NMR Analyzers

CHEN Shan-shan^1,2, XIA Tian², BI Xin², MIAO Zhi-ying¹, YANG Pei-qiang³, WANG Hong-zhi^1,2, DAI Shu-guang¹

1. Scool of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China;
2. Shanghai University of Medicine & Health Science, Shanghai, 201318, China;
3. Suzhou Niumag Corporation Ltd, Suzhou 215163, China

Received:2015-12-21 Revised:2017-01-04 Online:2017-03-05 Published:2017-03-05

摘要/Abstract

摘要： 磁场的高均匀性是高性能核磁共振弛豫分析仪实现短弛豫时间样品和微弱信号核磁共振（NMR）检测的基本保障.该文以0.45 T双极型永磁体作为设计核心部件，在大范围磁体空间-25.4 mm球空间（DSV）内，基于目标场法设计了X、Y、Z、XY、XZ、YZ、Z²共7组有源匀场线圈，根据线圈供电要求，设计了可编程恒流电源，搭建了可用于高性能核磁共振弛豫分析仪磁体的有源匀场系统，介绍了系统的基本结构、设计过程及匀场方法.实验测试结果验证了大范围磁体空间内该匀场系统的实用性.

关键词: 恒流源, 低场核磁共振(low-field NMR), 有源匀场, 目标场法, 自由感应衰减(FID)

Abstract: High homogeneity of the magnet field is an essential prerequisite for measuring weak signals and short spin-spin relaxation time on a nuclear magnetic resonance (NMR) analyzer. In this study, we designed active shimming coils, based on a target-field approach, for low filed NMR analyzers. Constant current source was designed according to the coil power supply. An active shimming platform used in a NMR analyzer's 0.45 T magnet system was constructed over a large target-diameter-sphere-volume (25.4 mm DSV) of interest. The basic structure and operation principles of the system, as well as the shimming method, were introduced. The feasibility and practicality of the design was demonstrated by experimental measurements.

Key words: constant current source, free induction decay (FID), target-field approach, low-field NMR, active shimming

中图分类号:

陈珊珊, 夏天, 毕昕, 苗志英, 杨培强, 汪红志, 戴曙光. 高性能核磁共振弛豫分析仪匀场系统的设计与实现[J]. 波谱学杂志, 2017, 34(1): 87-99.

CHEN Shan-shan, XIA Tian, BI Xin, MIAO Zhi-ying, YANG Pei-qiang, WANG Hong-zhi, DAI Shu-guang. Design and Implementation of An Active Shimming System for Low Field NMR Analyzers[J]. Chinese Journal of Magnetic Resonance, 2017, 34(1): 87-99.

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高性能核磁共振弛豫分析仪匀场系统的设计与实现

Design and Implementation of An Active Shimming System for Low Field NMR Analyzers

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