氚标记药物和生化试剂的氚核磁共振测定

波谱学杂志 ›› 1985, Vol. 2 ›› Issue (4): 311-316.

氚标记药物和生化试剂的氚核磁共振测定

郑冬珠, 袁建明, 蒋晓马

中国科学院上海原子核研究所

收稿日期:1985-01-08 修回日期:1985-07-27 出版日期:1985-12-05 发布日期:2018-01-23

DETERMINATION OF SOME TRITIATED PHARMACEUTICALS AND BIOCHEMICAL REAGENTS BY THE TRITIUM NUCLEAR MAGNETIC NESONANCE SPECTROSCOPY

Zheng Dongzhu, Yuan Jianming, Jiang xiaoma

shanghai Institute of Nuclear Research, Academia Sinica

Received:1985-01-08 Revised:1985-07-27 Online:1985-12-05 Published:2018-01-23

摘要/Abstract

摘要： 本文报道了用氚核磁共振测定氚化双氢心得舒等五钟定位氚标记化合物和非定位标记亮石松碱化合物中氚在分子中的位置及相对含量。并对[CH₃-³H]胸腺嘧啶和[4-³H]苯丙氨酸的未经质子去偶的³H-NMR谱进行解析,测出其氚氢间的偶合常数(J_HT),然后根据关系式:J_HH=J_HT(γ_H/γ_r)算出其磁全同质子-质子的偶合常数。

郑冬珠, 袁建明, 蒋晓马. 氚标记药物和生化试剂的氚核磁共振测定[J]. 波谱学杂志, 1985, 2(4): 311-316.

Zheng Dongzhu, Yuan Jianming, Jiang xiaoma. DETERMINATION OF SOME TRITIATED PHARMACEUTICALS AND BIOCHEMICAL REAGENTS BY THE TRITIUM NUCLEAR MAGNETIC NESONANCE SPECTROSCOPY[J]. Chinese Journal of Magnetic Resonance, 1985, 2(4): 311-316.