利用液体核磁共振技术解析核酸四链体结构

doi:10.11938/cjmr20150202

摘要/Abstract

摘要：

富含G 碱基的DNA 和RNA 序列能够形成四股的G-四链体．基于液体核磁共振波谱在G-四链体结构、动力学、相互作用研究中的核心地位，该综述详细回顾阐述
了G-四链体结构和相互作用研究中的核磁共振方法、技术和进展．

Abstract:

Abstract：G-rich repetitive DNA and RNA sequences can form four-stranded structures named G-quadruplexes. Solution NMR spectroscopy has played a central role in examining G-quadruplex structure, dynamics, and interaction. Here we review NMR methods to study structure and interaction of G-quadruplexes.

Key words: NMR spectroscopy, G-quadruplex, DNA, RNA

中图分类号:

O482.53

刘长东，朱广. 利用液体核磁共振技术解析核酸四链体结构[J]. 波谱学杂志, 2015, 32(2): 150-162.

LIU Chang-dong，ZHU Guang. Quadruplex Nucleic Acid Structure Determination by Solution NMR[J]. Chinese Journal of Magnetic Resonance, 2015, 32(2): 150-162.

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