基于残留偶极耦合对西松烷二萜化合物sinulariol Z立体化学的研究

石星, 张越, 张秀丽, 王聪

Stereochemical Research on Cembranes Diterpenoid Sinulariol Z Based on Residual Dipolar Couplings

SHI Xing, ZHANG Yue, ZHANG Xiuli, WANG Cong

表1 Sinulariol Z的实验和理论RDC值

Table 1 Experimental and theoretically predicted RDCs of sinulariol Z

Position Sinulariol Z Exp. 1DCH/Hz Calc. 1DCH/Hz (S*S*S*R*) C2-H2 8.104 8.74 C3-H3 10.54 9.49 C6-H6a -16.524 -10.51 C9-H9a 0.79 3.24 C9-H9b -1.346 1.96 C11-H11 9.572 10.15 C15-H15 1.614 3.53 C16-H16 -0.92 1.63 C17-H17 0.572 0.34 C18-H18 -3.562 -1.93 C19-H19 2.486 2.93 C20-H20 -2.15 -2.08