海博麦布结构确证

徐肖杰,陈延安,李旭飞,张云才,张勇,詹冬凯,潘婷

Structural Elucidation of Hybutimibe

XU Xiaojie,CHEN Yan’an,LI Xufei,ZHANG Yuncai,ZHANG Yong,ZHAN Dongkai,PAN Ting

图2 海博麦布的合成路径.TsOH：对甲苯磺酸；TsNHNH2:对甲苯磺酰肼；DBU：1,8-二偶氮杂双螺环[5.4.0]十一-7-烯；DMAc: N, N-二甲基乙酰胺；DIPEA：N,N-二异丙基乙胺；BSA：N, O-双（三甲基硅基）乙酰胺；TBAF：四丁基氟化铵

Fig. 2 Synthetic route of hybutimibe. TsOH: p-toluenesulfonic acid; TsNHNH2: p-toluenesulfonyl hydrazide; DBU: 1,8-diazabicyclo [5.4.0]undec-7-ene; DMAc: N, N-dimethylacetamide; DIPEA: N,N-diisopropylethylamine; BSA: N,O-bis(trimethylsilyl)acetamide; TBAF: Tetrabutylammonium fluoride