磁共振波谱技术在吸烟对大脑影响的研究进展

李任,常晓,张捷,张孝勇

Progress of Magnetic Resonance Spectroscopy in the Study of the Effects of Smoking on the Brain

LI Ren,CHANG Xiao,ZHANG Jie,ZHANG Xiaoyong

表2 本文中提及的研究所采用的MRS技术、序列、软件以及感兴趣的脑区和代谢物变化文献综述

Table 2 Literature summary of the MRS technologies, pulse sequences, processing softwares, and the metabolites changes in the brain region of interest

文献序号 技术 磁场强度 序列 处理软件 脑区 代谢物变化 [20] 1H-MRS 3.0 T PRESS Program package* HC\ACC 吸烟者NAA降低 [21] 1H-MRS 3.0 T PRESS LCModel ACC 吸烟者Glu、NAA、Cr、mI降低 [22] 1H-MRS 4.0 T\1.5 T STEAM Program package* DLPFC\ACC 吸烟者Glu、NAA、Cr、mI降低 [23] 1H-MRS 3.0 T MEGA-PRESS LCModel dACC 吸烟者Glu、Gln增加 [24] 1H-MRS 2.1 T J-editing sequence Program package* Occipital cortex 雌性GABA/Cr降低 [25] 1H-MRS 7.0 T PRESS LCModel HC 雄性NAA、mI降低 [26] 1H-MRS 7.0 T PRESS LCModel HC\ACC\NAC 雄性GABA、Tau、NAA、Cr增加 [27] 31P-MRS 3.0 T Chemical shift imaging free induction decay pulse sequence jMRUI ACC 雌性PCr增加 [28] 1H-MRS 3.0 T PRESS LCModel dACC 戒断期间Glu/Cr降低 [29] 1H-MRS 4.0 T 2D-JPRESS LCModel dACC 易复发组Glu/Cr降低 [30] 1H-MRS 3.0 T J-editing sequence LCModel NAC 戒断期间mI+Gly增加 [31] 1H-MRS 3.0 T PRESS LCModel HC\dACC 吸烟者Cho/Cr降低 [33] 1H-MRS 3.0 T PRESS LCModel Insular cortex 吸烟者Glu、Gln增加 [36] 1H-MRS 2.1 T J-editing sequence LCModel Occipital cortex 吸烟者Glu、Gln增加 [37] 1H-MRS 3.0 T PRESS LCModel HC\ACC BD吸烟者GSH降低 [38] 1H-MRS 3.0 T PRESS LCModel ACC 吸烟频率减少GSH增加