细胞色素c甲硫氨酸氧化机制的NMR研究

赵蓓蓓,占建华,胡琴,朱勤俊,刘买利,张许

NMR Study on the Mechanism of Cytochrome c Methionine Oxidation

ZHAO Beibei,ZHAN Jianhua,HU Qin,ZHU Qinjun,LIU Maili,ZHANG Xu

表1 ChemDraw计算模拟的不同氧化程度Met末端甲基的化学位移

Table 1 Similated chemical shifts of the terminal methyl groups of methionine with or without oxidative modification by ChemDraw

Molecules δH of the terminal methyl δC of the terminal methyl Met 2.07 15.4 亚砜化Met 2.50 38.4 砜化Met 2.80 43.8