溶液中ATAD2溴结构域聚集行为的研究

王远方,王小花,舒畅,张许,刘买利,曾丹云

The Aggregation of ATAD2 Bromodomain in Solution

WANG Yuanfang,WANG Xiaohua,SHU Chang,ZHANG Xu,LIU Maili,ZENG Danyun

图5 (a) ATAD2溴结构域的不同温度孵育8 h前后1H NMR谱图，初始状态（蓝色），孵育8 h状态（红色）；(b) ATAD2溴结构域不同pH下的CD谱图；(c) ATAD2溴结构域在不同离子强度溶液的CD谱图

Fig. 5 (a) 1H NMR spectra of ATAD2 bromodomain incubated at different temperatures. Initial state (blue), incubation state for 8 h (red); (b) The CD spectra of ATAD2 bromodomain at different pH; (c) The CD spectra of ATAD2 bromodomain at different salt concentrations