溶液中ATAD2溴结构域聚集行为的研究 |
王远方,王小花,舒畅,张许,刘买利,曾丹云 |
The Aggregation of ATAD2 Bromodomain in Solution |
WANG Yuanfang,WANG Xiaohua,SHU Chang,ZHANG Xu,LIU Maili,ZENG Danyun |
图3 (a) ATAD2溴结构域的1H- 15N HSQC谱图: ATAD2溴结构域初始状态NMR谱(蓝色),25 ℃孵育8 h后的ATAD2溴结构域NMR谱(红色);(b) ATAD2溴结构域部分NMR信号随时间的变化;(c) ATAD2溴结构域中代表谱峰强度随时间的变化 |
Fig. 3 (a) 1H- 15N HSQC spectra of ATAD2 bromodomain: The NMR spectrum of the initial ATAD2 bromodomain sample (blue), the NMR spectrum of the sample incubated at 25 ℃ for 8 h (red); (b) The representative NMR signals of ATAD2 bromodomain over time; (c) The intensities of representative NMR signals of ATAD2 bromodomain over time |