新型吡唑并[3,4-d]嘧啶-4-酮类衍生物的结构表征和镇痛活性
翟重钢,汪鹏程,单玉宝,兰昱,胡锐,杨运煌

Structure Characterization and Analgesic Activity of Novel Pyrazolo[3,4-d]pyrimidin-4-one Derivatives
ZHAI Chonggang,WANG Pengcheng,SHAN Yubao,LAN Yu,HU Rui,YANG Yunhuang
表3 化合物C的1H NMR实验数据(溶剂:DMSO-d6
Table 3 1H NMR experimental data of compound C (solvent: DMSO-d6)
编号 δH 氢原子个数 谱峰裂分(J/Hz) 归属
1 1.95 2 p (6.6) H-14
2 2.28 3 s H-16
3 2.31 3 s H-17
4 2.52 2 t (7.0) H-15
5 2.55 4 t (6.8) H-18, H-21
6 2.64 3 s H-12
7 3.13 4 t (5.5) H-19, H-20
8 4.29 2 t (6.2) H-13
9 6.77 1 t (7.3) H-25
10 6.93 2 d (8.1) H-23, H-27
11 7.21 2 dd (8.7/7.2) H-24, H-26
12 7.30 1 d (8.2) H-2
13 7.71 1 dd (8.2/2.3) H-1
14 7.75 1 d (2.3) H-5
15 8.31 1 s H-9