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非天然氨基酸在蛋白质动态特性核磁共振研究中的应用
史朝为,石攀,田长麟*()
NMR Studies of Large Protein Dynamics Using Unnatural Amino Acids
Chao-wei SHI,Pan SHI,Chang-lin TIAN*()

图1. 在蛋白质中引入非天然氨基酸的标记方法.红色为核磁共振可检测的氨基酸或原子核,蓝色为天然非标记氨基酸

Fig.1. Unnatural amino acids (UAA) labeling strategies for proteins. NMR active nuclei or residues are shown in red, and the other unlabeled natural residues are shown in blue