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靶向肿瘤因子c-MYC基因启动区G4-DNA的小分子药物设计及核磁共振研究进展
胡晓东,蓝文贤,王春喜,曹春阳*()
Research Advance and NMR Studies of Anti-Cancer Small Molecules Targeting c-MYC G4-DNA
Xiao-dong HU,Wen-xian LAN,Chun-xi WANG,Chun-yang CAO*()

图9. vegfr-2 17T G4-DNA的溶液结构.(a)飘带图,(b) carton示意图.其中,紫色表示syn构象的碱基G,蓝色表示anti构象的碱基G,黄色表示G-C碱基对[59]

Fig.9. Solution structure of vegfr-2 17T G4-DNA displayed in ribbon mode (a) and cartoon mode (b), respectively, in which syn-G bases are shown in purple, anti-G bases are shown in cyan, G-C base-pairs are shown in yellow[59]