靶向肿瘤因子c-MYC基因启动区G4-DNA的小分子药物设计及核磁共振研究进展
胡晓东,蓝文贤,王春喜,曹春阳*(
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Research Advance and NMR Studies of Anti-Cancer Small Molecules Targeting c-MYC G4-DNA
Xiao-dong HU,Wen-xian LAN,Chun-xi WANG,Chun-yang CAO*()
)
图5. 与c-MYC G4相互作用的蛋白的结合方式.提升(a)和稳定(b)G4结构稳定性结合方式；(c)解螺旋G4结构的结合方式
Fig.5. Binding modes of the proteins interacting with c-MYC G4. Binding modes that promotes (a) and stabilizes (b) the G4 structural stability; (c) Binding mode that unwinds G4 structure
