组织蛋白酶B响应的超极化129Xe MRI探针对肺癌细胞的超灵敏探测
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王崇武 1,2,黄曦 1,石磊 1,陈世桢 1,周欣 1,*( )
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Cathepsin B Triggered Hyperpolarization 129Xe MRI Probe for Ultra-Sensitive Lung Cancer Cells Detection
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Chong-wu WANG 1,2,Xi HUANG 1,Lei SHI 1,Shi-zhen CHEN 1,Xin ZHOU 1,*( )
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图2. (a) 2 μmol/L和(b) 5 μmol/L的探针a与Cat B反应前后的129Xe Hyper-CEST信号
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Fig.2. 129Xe Hyper-CEST signals of probe a with concentrations of (a) 2 μmol/L and (b) 5μmol/L before and after reaction with Cat B
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