盐酸四环素中可交换氢和氢键的核磁共振波谱研究
谢金华1,王乐1,*(
),刘盼1,苏稀琪1,MINGLi-June2,3
),刘盼1,苏稀琪1,MINGLi-June2,3
An NMR Spectroscopy Study on the Exchangeable Protons and Hydrogen Bonds in Tetracycline Hydrochloride
Jin-hua XIE1,Le WANG1,*(),Pan LIU1,Xi-qi SU1,Li-June MING2,3
),Pan LIU1,Xi-qi SU1,Li-June MING2,3
图1. 盐酸四环素类衍生物结构式：盐酸甲稀土霉素（1A），R1=OH，R2/R3=CH2；盐酸土霉素（1B），R1=R3=OH，R2=Me；盐酸四环素（1C），R1=H，R2=Me，R3=OH
Fig.1. Structural formula of tetracycline hydrochloride derivatives. Metacycline hydrochloride (1A): R1=OH, R2/R3=CH2; Oxytetracycline hydrochloride (1B): R1=R3=OH, R2=Me; Tetracycline hydrochloride (1C): R1=H, R2=Me, R3=OH
