Detection of Liver Fibrosis Using Magnetic Resonance Elastography

Detection of Liver Fibrosis Using Magnetic Resonance Elastography

WANG Hong-zhi^1,2,5*, LIU Xiang^1, WANG He³, CHEN Shan-shan^1,5, HUANG Qing-ming^1,5, WANG Xiao-yan⁴, LU Lun⁴, HUANG Yong^1,5, CHENG Hong-yan⁴, LI Geng-ying², ZHANG Xue-long^1,5

1. Graduate of Medical Imaging Technology, University of Shanghai Science and Technology, Shanghai 200093, China;
2. Shanghai Key Laboratory of Magnetic Resonance Technology, Department of Physics, East China Normal University, Shanghai 200062, China； 
3. GE Healthcare (China), Shanghai 201203, China;
4. Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China;
5. Shanghai Medical Instrument College, Shanghai 200093, China

Received:2012-08-30 Revised:2012-09-26 Online:2013-06-05 Published:2013-06-05
About author:Wang Hong-zhi,Tel: 021-65502671，E-mail: wanghzhi2000@sina.com.
Supported by:
上海市科研创新基金重点资助项目（10YZ237）.

Abstract

Abstract:

Magnetic resonance elastography can be used to measure the elastic stress of the liver and the extent of hepatic fibrosis quantitatively. This paper describes the principles and practical implementation of magnetic resonance elastography, including tissue biomechanical model analysis, development of the shear wave developing stimulator, design of elastic imaging sequence and fitting algorithms for elastography. Magnetic resonance elastography measurements on ex vivo pork liver and human volunteers were demonstrated experimentally.

Key words: magnetic resonance elastography, hepatic fibrosis, local frequency estimation, elasticity, liver

CLC Number:

O482.53

WANG Hong-zhi1,2,5*, LIU Xiang1, WANG He3, CHEN Shan-shan1,5, HUANG Qing-ming1,5, WANG Xiao-yan4, LU Lun4, HUANG Yong1,5, CHENG Hong-yan4, LI Geng-ying2, ZHANG Xue-long1,5. Detection of Liver Fibrosis Using Magnetic Resonance Elastography[J]. Chinese Journal of Magnetic Resonance.

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