Chinese Journal of Magnetic Resonance ›› 2010, Vol. 27 ›› Issue (3): 417-424.

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Probabilistic Language Pathways Based HARDI Tractography

 CHEN Ke-Hsin1, FAN Hsin-Ya1, TSAO Su-Ping1, CHAO Yi-Ping1,2, LIN Ching-Po1   

  1. 1. Institute of Neuroscience, National Yang Ming University, Taipei 11221;
    2. School of Applied Information Sciences, Chung Shan Medical University, Taichung 40201
  • Received:2010-07-31 Online:2010-09-05 Published:2010-09-05

Abstract:

Neuroanatomical connection is crucial to the understanding of brain function. The language anatomical model proposed that Broca’s area located in the inferior frontal lobe and Wernicke’s area located in the superior temporal gyrus, both were connected through the arcuate fasciculus, which functions in fast, automatic word repetition. Furthermore, the supramarginal gyrus has been highlighted the importance for phonological processing in recent neuroimaging studies. Diffusion MRI is a non-invasive technique for in vivo measurement of microstructural properties of brain white matter. Integrated with fiber tractography algorithm, there can be visualized the three-dimensional (3D) pathways of white matter tracts. The aim of this study is to visualize the corticocortical connection of language areas in the human brain via high angular resolution diffusion imaging and tractography.

Key words: diffusion tensor imaging, high angular resolution diffusion imaging, tractography, language pathway

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