Spin Trapping-ESR Study on Free Radicals in Cigarette Smoke

Abstract

Abstract:

It is known that free radicals in cigarette smoke do harm to the human health. The most common way to detect the reactive free radicals is electron spin resonance (ESR) spectroscopy in conjunction with the spin trapping method. In this paper with a highly efficient and novel spin trap DEPMPO, the alkyl radicals and hydroxyl radical were obtained in the aqueous medium, among of which no adducts of alkoxyl radicals were discovered. In view of the fact that more oxygen molecule dissolved in organic solvents as well as the priority of the ability of DEPMPO in capturing reactive free radicals and its character of ESR spectrum to those of PBN and DMPO, we considered that the trapped alkoxyl radicals in the previous paper may derive from the secondary radical products by oxidation of alkyl radicals.

Key words: cigarette smoke, radicals, spin trapping, ESR, DEPMPO

CLC Number:

O482.53

LV Yu-Guang, Yan-Bao-Zhen, Tian-Qiu, Zhao-Ming-Yue, Nie-Cong, ZENG Bei, LIU Yang-Peng, Liu-Yang. Spin Trapping-ESR Study on Free Radicals in Cigarette Smoke[J]. Chinese Journal of Magnetic Resonance, 2005, 22(1): 21-25.

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