Chinese Journal of Magnetic Resonance ›› 2018, Vol. 35 ›› Issue (1): 90-97.doi: 10.11938/cjmr20172583

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Structural Elucidation and NMR Spectral Assignments of Two C19-Diterpenoid Alkaloids

YIN Tian-peng1,2, CHEN Yang1, LUO Ping2, CAL Le2, DING Zhong-tao2   

  1. 1. Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine, Zunyi Medical University Zhuhai Campus, Zhuhai 519041, China;
    2. Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
  • Received:2017-05-30 Online:2018-03-05 Published:2018-03-05
  • Supported by:
    The national natural science foundation of China (81460648); Graduate student quality curriculum of Yunnan university.

Abstract: Two C19-diterpenoid alkaloids, homochasmanine (compound 1) and 14-debenzoylfranchetine (compound 2), were isolated from the roots of Aconitum handelianum. Their structures were elucidated by one-dimensional and two-dimensional nuclear magnetic resonance (NMR) techniques, including 1H NMR, 13C NMR, DEPT, 1H-1H COSY, HSQC, HMBC and NOESY. The 1H and 13C NMR signals of the compounds were completely assigned.

Key words: NMR, elucidation, assignment, diterpenoid alkaloid, Aconitum handelianum

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