Chinese Journal of Magnetic Resonance

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Applications of New Two-Dimensional NMR Spectroscopy in Natural Products Research

WANG Bei,LIU Xing,ZHU Guo-lei,LI Hai-zhou*   

  1. Phytochemistry Laboratory, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China
  • Received:2012-10-08 Revised:2013-05-06 Online:2013-12-05 Published:2013-12-05
  • About author:*Corresponding author: Li Hai-zhou, Tel: 0871-65920657, E-mail: lihaizhou@yninfo.com.
  • Supported by:

    国家自然科学基金资助项目(31060054).

Abstract:

Two-dimensional NMR spectroscopy is frequently used in natural products research for structure elucidation and studies on structure-activity relationship. In this article, the commonly used two-dimensional NMR spectroscopy techniques for natural products research are reviewed. The merits of each technique are discussed. In particular, the new two-dimensional NMR spectroscopy methods/experiments emerging in recent years (i.e., H2BC, new H2BC, HAT HMBC and HSQC-ADEQUATE) and their applications in natural products research are introduced in detail.

Key words: two-dimensional NMR spectroscopy, H2BC, new H2BC, HAT HMBC, HSQC-ADEQUATE

CLC Number: