Interactions Between NP-10 and Single/Double Chain Quaternary Ammonium Salts Studied by NMR Spectroscopy

doi:10.11938/cjmr20170103

Abstract

Abstract: NMR spectroscopy was used to study the behaviors of three binary surfactant micellar solutions, NP-10/DTAC, NP-10/C₁₂-C₄-C₁₂ and NP-10/C₁₂-C₈-C₁₂ respectively. Relative arrangement and the sites of interactions between the surfactant molecule pairs in the mixed micelles, as well as the differences in inter-/intra- molecular interactions were investigated. 2D NOESY experiments revealed that the number of sites of interaction varied across the different binary mixtures, and the degree of interactions increased in the following order:NP-10/C₁₂-C₈-C₁₂ > NP-10/C₁₂-C₄-C₁₂ > NP-10/DTAC. Self-diffusion coefficient experiments showed that the influence of NP-10 on the hydro-dynamic radius of the mixed micelles was greater than that of quaternary ammonium salts. Spin-spin relaxation time experiments indicated that, for NP-10/DTAC and NP-10/C₁₂-C_s-C₁₂ (s=4 or 8) binary systems, intra-molecular interactions dominated and inter-molecular interactions began to decrease at molar ratios 1:3 and 1:2. These points corresponded to the optimal molar ratio for synergic effects. Spatial distance measurements supported this result, confirmed that the optimal molar ratio was 1:3 and 1:2.

Key words: NMR, interaction, single chain double chain quaternary ammonium, NP-10

CLC Number:

O482.53

MA Er-qian, LI Yong-xiao, ZHAO Rui-ge, ZHANG Zhan-hui, YANG Qiu-qing. Interactions Between NP-10 and Single/Double Chain Quaternary Ammonium Salts Studied by NMR Spectroscopy[J]. Chinese Journal of Magnetic Resonance, 2017, 34(1): 16-24.

References

[1] TRAWINSKA A, HALLMANN E, MEDRZYCKA K. Synergistic effects in micellization and surface tension reduction in nonionic gemini S-10 and cationic RTAB surfactants mixtures[J]. Colloids and Surfaces A:Physicochem Eng Aspects, 2016, 488:162-172.
[2] SIDDIQUI H, KAMIL M, PANDA M, et al. Solubilization of phenanthrene and fluorene in equimolar binary mixtures of gemini/conventional surfactants[J]. Chinese J Chem Eng, 2014, 22(9):1009-1015.
[3] CARDOSO A M, MORAIS C M, CRUZ A R, et al. New serine-derived gemini surfactants as gene delivery systems[J]. Eur J Pharm Biopharm, 2015, 89:347-356.
[4] HU Z Y, WANG L Q, GUO J F, et al. Interaction of a novel anionic gemini surfactant containing a triazine ring with cetyltrimethyl ammonium bromide in aqueous solution[J]. J Surfact Deterg, 2015, 18(1):17-24.
[5] LIU J, JIANG Y, CHEN H, et al. Probing dynamics and mechanism of exchange process of quaternary ammonium dimeric surfactants, 14-s-14, in the presence of conventional surfactants[J]. J Phys Chem B, 2012, 116(51):14859-14868.
[6] JIANG Y, CHEN H, CUI X H, et al. ¹H NMR study on pre-micellization of quaternary ammonium gemini surfactants[J]. Langmuir, 2008, 24(7):3118-3121.
[7] JIANG Y, LU X Y, CHEN H, et al. NMR study of the dynamics of cationic gemini surfactant 14-2-14 in mixed solutions with conventional surfactants[J]. J Phys Chem B, 2009, 113(24):8357-8361.
[8] ZHANG J Z, XIE L, CHAI S G, et al. Interaction in binary mixtures of gemini surfactant G12-6-12 and CTAB by NMR[J]. Chinese J Chem Phys, 2014, 27(3):307-314.
[9] XANG X Y, TANG X L, CHENG G Z, et al. Mixed micelles of sodium 4-decyl naphthalene sulfonate with Triton X-100 and sodium dodecyl sulfonate analyzed by ¹H NMR[J]. J Colloid Interf Sci, 2004, 279(2):533-538.
[10] DEL BURGO P, JUNQUERA E, AICART E. Mixed micellization of a nonionic-cationic surfactant system constituted by n-octyl-β-Dglucopyranoside/dodecyltrimethylammonium bromide/H₂O. An electrochemical, thermodynamic, and spectroscopic study[J]. Langmuir, 2004, 20(5):1587-1596.
[11] YANG Q Q, ZHOU Q, SOMASUNDARAN P. Mixed micelles of octane-1,8 bis(dodecyl dimethyl ammonium chloride) and n-dodecyl-β- maltoside by ¹H NMR study[J]. Colloids and Surfaces A:Physicochem Eng Aspects, 2007, 305(1-3):22-28.
[12] YANG Q Q, ZHOU Q, SOMASUNDARAN P. NMR study of micellar microstructures of cationic single-chain and gemini surfactants and their mixtures with nonionic surfactant n-dodecyl-β-maltoside[J]. Colloids and Surfaces A:Physicochem Eng Aspects, 2008, 322(1-3):40-46.
[13] LIN J H, CHEN W S, HOU S S. NMR studies on effects of tetraalkyl ammonium bromides on micellization of sodium dodecylsulfate[J]. J Phys Chem B, 2013, 117(40):12076-12085.
[14] ARKHIPOV V P, IDIYATULLIN Z S, POTAPOVA E F, et al. Micelles and aggregates of oxyethylated isononylphenols and their extraction properties near cloud point[J]. J Phys Chem B, 2014, 118(20):5480-5487.
[15] RAUWEL G, LECLERCQ L, CRIQUELION J, et al. Aqueous mixtures of di-n-decyldimethylammonium chloride/polyoxyethylene alkyl ether:Dramatic influence of tail/tail and head/head interactions on co-micellization and biocidal activity[J]. J Colloid Interf Sci, 2012, 374(1):176-186.
[16] SONG Y Q. Low field magnetic resonance:Multi-dimensional experiments of relaxation and diffusion[J]. Chinese J Magn Reson, 2015, 32(2):141-149.
[17] PODO F, RAY A, NEMETHY G. Structure and hydration of nonionic detergent micelles. High resolution nuclear magnetic resonance study[J]. J Am Chem Soc, 1973, 95(19):6164-6170.
[18] YUAN H Z, DU Y R, ZHAO S, et al. Self-aggregation of surfactants in water solution by NMR[J]. Sci China Ser A, 1999, 42(3):319-323.
[19] GAO H C, FANG X W, MAO S Z, et al. Conformation and dynamics of polyoxyethylene lauryl ether (Brij-35) chains in aqueous micellar solution studied by 2D NOESY and ¹H NMR relaxation[J]. Sci China Ser B, 2002, 45(2):143-150.
[20] YANG Q Q, ZHOU Q, SOMASUNDARAN P. ¹H NMR study of micelles formed by mixture of nonionic n-dodecyl-β-D-maltoside and cationic gemini surfactants[J]. J Mol Liq, 2009, 146(3):105-111.
[21] LIU C D, ZHU G. Quadruplex nucleic acid structure determination by solution NMR[J]. Chinese J Magn Reson, 2015, 32(2)