白花刺参中的咖啡酰基奎宁酸成分

波谱学杂志

白花刺参中的咖啡酰基奎宁酸成分

滕荣伟¹，周志宏²，王德祖¹，杨崇仁^1*

1.中国科学院昆明植物研究所，云南昆明 650204;
2.昆明生物谷医药研究所，云南昆明 650108

收稿日期:2001-08-13 修回日期:2001-11-05 出版日期:2002-06-05 发布日期:2002-06-05
作者简介:滕荣伟（1975-），男，博士，植物化学专业；E-mail：tengrongwei@hotmail.com *通讯联系人：E-mail：cryang@public.km.yu.cn.

FOUR CAFFEOYLQUINIC ACIDS FROM MORINA NEPALENSIS VAR. ALBA HAND.-MAZZ.

TENG Rong-wei¹, ZHOU Zhi-hong², WANG De-zu¹, YANG Chon g-ren^1*

1.Kunming Institute of Botany, Chinese Academy of Sciences, Kuming 650204, China;
2.Kungming Institute of Medicine of Biologic Valley, Kunming 650108, China

Received:2001-08-13 Revised:2001-11-05 Online:2002-06-05 Published:2002-06-05
About author:*Correspondence author: E-mail：cryang@public.km.yu.cn.

摘要/Abstract

摘要：

著名藏药白花刺参Morina nepalensis var. alba Hand. Mazz.的全株的水溶性部分通过硅胶、RP-8、Sephadex LH-20柱层析分离，得到4个咖啡酰基奎宁酸1～4 ,运用光谱和波谱方法, 分别鉴定为3-O-咖啡酰基奎宁酸（1）、3, 5-O-双咖啡酰基奎宁酸（2）、3, 4-O-双咖啡酰基-奎宁酸（3）和4, 5-O-双咖啡酰基-奎宁酸（4）. 应用2D NMR图谱, 对其氢和碳的化学位移进行全归属, 并报道1, 2在氘代甲醇和氘代二-甲亚砜两种溶剂下测定¹H和¹³C化学位移. 4个化合物都是首次分离自刺参属植物.

关键词: 白花刺参, 川续断科, 咖啡酰基奎宁酸, NMR全归属

Abstract:

Four compounds were isolated from water-soluble part of whole plant of Morina nepalensis var. alba Hand.-Mazz.by CC on Si gel, RP-8, Sephadex LH-20. Based on spectroscopic evidences, their structures were elucidated as 3-O-caffeoyl-quinic acid (1), 3, 5-O-dicaffeoyl-quinic acid (2), 3, 4-O- dicaffeoyl-quinic acid (3] ) and 4, 5-O- dicaffeoyl-quinic acid (4), respectively. Complet e assignments of ¹H and ¹³C spectra of these four compounds were obtained by 2D NMR spe ctra. Furtherm ore, ¹H and ¹³C Chemical shifts of compound 1 and 2 were determined with both in CD₃OD and DMSO-d₆ solvent. All four compounds were firstly isolated from the Morin a plants.

Key words: morina nepalensis var. alba Hand.-Mazz, dipsacaceae, morina, caffeo ylquinic acids, NMR complete assignments

中图分类号:

O641

滕荣伟1，周志宏2，王德祖1，杨崇仁1*. 白花刺参中的咖啡酰基奎宁酸成分[J]. 波谱学杂志.

TENG Rong-wei1, ZHOU Zhi-hong2, WANG De-zu1, YANG Chon g-ren1*. FOUR CAFFEOYLQUINIC ACIDS FROM MORINA NEPALENSIS VAR. ALBA HAND.-MAZZ.[J]. Chinese Journal of Magnetic Resonance.

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