定量磁化率成像重建方法及其应用

波谱学杂志

定量磁化率成像重建方法及其应用

王阿莉1，林建忠2，刘伟骏3，蔡聪波3*，陈忠1

1. 厦门大学电子科学系，福建省等离子体与磁共振研究重点实验室，福建厦门 361005；
2. 厦门大学附属中山医院，福建厦门 361005；
3. 厦门大学通信工程系，福建厦门 361005

收稿日期:2013-11-06 修回日期:2013-11-30 出版日期:2014-03-05 发布日期:2014-03-05
作者简介:王阿莉(1988-)，女，安徽界首人，硕士研究生，从事核磁共振新技术及应用方面的研究．*通讯联系人：蔡聪波，电话：0592-2087539, E-mail: cbcai@xmu.edu.cn.
基金资助:
国家自然科学基金资助项目(81171331, 11174239)，中央高校基本业务费资助项目(2010121101)．

Quantitative Susceptibility Mapping

WANG A-li1，LIN Jian-zhong2，LIU Wei-jun3，CAI Cong-bo3*，CHEN Zhong1

1. Department of Electronic Science, Xiamen University, Fujian Key Laboratory of Plasma and Magnetic Resonance, Xiamen 361005, China;
2. Zhongshan Hospital Xiamen University, Xiamen 361005, China;
3. Department of Communication Engineering, Xiamen University, Xiamen 361005, China

Received:2013-11-06 Revised:2013-11-30 Online:2014-03-05 Published:2014-03-05
About author:*Corresponding author：CAI Cong-bo, Tel: 0592-2087539, E-mail: cbcai@xmu.edu.cn.
Supported by:
国家自然科学基金资助项目(81171331, 11174239)，中央高校基本业务费资助项目(2010121101)．

摘要/Abstract

摘要：

磁共振成像(MRI)中，相位图像包含丰富的组织磁化率变化信息，获取相位图像不需要额外的扫描时间．组织中的顺磁性物质会影响组织磁化率差异，从而导致局部磁场不均匀．对组织内顺磁性物质的定量有利于许多脑血管疾病和神经系统疾病的诊断，但利用局部相位信息重建组织磁化率分布是一个不适定逆问题，目前仍然有许多问题亟待解决．该文着重介绍定量磁化率成像(QSM)的原理、重建方法及其在MRI 中的应用．

关键词: 定量磁化率成像(QSM), 图像重建, 背景磁场, 相位图

Abstract:

Phase images of magnetic resonance imaging (MRI) contain abundant information about local susceptibility changes among different types of tissues, and getting phase images requires no additional scan time. The diagnosis of cerebrovascular diseases and nervous system diseases may benefit from the quantification of paramagnetic substances in tissues. Quantitative susceptibility mapping (QSM), which uses the local phase information, has become a hot topic in basic and clinical studies. Paramagnetic substances in tissues cause local susceptibility changes and lead to local inhomogeneous magnetic field. However, the reconstruction of susceptibility distribution from induced magnetic field is an ill-posed inverse problem, and there are still many problems to be
solved at present. This article focuses on the theory of QSM, reconstruction methods and its applications in MRI.

Key words: QSM, image reconstruction, background magnetic field, phase image

中图分类号:

O482.53

王阿莉1，林建忠2，刘伟骏3，蔡聪波3*，陈忠1. 定量磁化率成像重建方法及其应用[J]. 波谱学杂志.

WANG A-li1，LIN Jian-zhong2，LIU Wei-jun3，CAI Cong-bo3*，CHEN Zhong1.

Quantitative Susceptibility Mapping

[J]. Chinese Journal of Magnetic Resonance.

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