波谱学杂志

• 研究论文 • 上一篇    下一篇

木根黄芩中—新黄酮的光谱特征

张永煜,宋爱华,马场正树,冈田嘉仁,奥山桥本和则,池谷幸信,冈田稔   

  1. 沈阳药科大学,沈阳 110015,中国;明治药科大学,东京 204-8588,日本;ツムラ中央研究所, 茨城 300-11,日本
  • 收稿日期:2001-02-05 修回日期:2001-03-19 出版日期:2001-06-05 发布日期:2001-06-05
  • 作者简介:张永煜(1955-),博士,研究员

SPECTRAL SPECIFICITY OF A NEW FLAVONOID FROM SCUTELLARIA PLANIPES

ZHANG Yong-yu, SONG Aihua, BABA Masaki, OKADA Yoshihito, OKUYAMA Toru, HASHIMOTO Kadsunori, IKEYA Yukinobu, OKADA Minoru   

  1. Shenyang Pharmaceutical University, Shenyang 110015, China; BABA Masaki, OKADA Yoshihito and OKUYAMA Toru; Meiji Pharmaceutical University, Tokyo 204-8588, Japan; HASHIMOTO Kadsunori, IKEYA Yukinobu and OKADA Minoru; Tsumura Central Laboratories, Tsumura and Co., lbaraki 300-11, Japan
  • Received:2001-02-05 Revised:2001-03-19 Online:2001-06-05 Published:2001-06-05

摘要:

从木根黄芩(Scutellaria planipes Nakai et Kitag.)中分离得到一新黄酮类化合物. 该化合物被鉴定为5,7,3′,6′-tetrahydroxy-6,8,2′-trimethoxyflavone. 它有很强的抑制5-酯氧合酶活性. 由于该化合物的A环全部被取代,因此,应用一般的光谱技术很难准确归属各碳的化学位移. 我们应用13C-13C相关谱和酰化位移方法,明确归属了各碳的信号,并订正了文献中对部分信号的错误归属.

关键词:

Abstract:

A new compound was isolated from the roots Scutellaria planipes (L.) and identified to be 5,7,3′,6′-tetrahydroxy-6,8,2′-trimethoxyflavone. It shows strong inhibitory effect for 5-lipoxygenase. All of the carbon signals were recognized and some assignment errors of similar compounds in the literature were corrected.

Key words: Scutellaria planipes,  5,7,3′,6′-tetrahydroxy-6,8,2′-trimethoxyflavone, Flavonoid

中图分类号: